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FLASH GENE
Symbol JTB contributors: KTN/npt - updated : 02/12/2008
HGNC name jumping translocation breakpoint
HGNC id 6201
Location 1q21.3      Physical location : 153.946.746 - 153.950.451
Synonym name
  • prostate androgen-regulated gene
  • PAR protein
  • Synonym symbol(s) PAR, hJT, HJTB, HSPC222
    DNA
    TYPE functioning gene
    STRUCTURE 3.71 kb     5 Exon(s)
    Genomic sequence alignment details
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status confirmed
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    5 - 1574 16.2 146 - -
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestivepancreas exocrine   moderately
     salivary gland   moderately
    Hearing/Equilibriumear   highly
    Reproductivefemale systemuteruscervix highly
     female systemovary  highly
    Respiratorylung   moderately
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Blood / hematopoieticbone marrow  highly
    cell lineage
    cell lines prostatic carcinoma
    fluid/secretion predominantly in lymph
    at STAGE
    physiological period fetal
    Text highly in umbilical cord
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a 30 aa signal peptide
  • HOMOLOGY
    interspecies homolog to dog JTB (87.7 pc)
    homolog to chimpanzee JTB (100 pc)
    homolog to cow JTB (89.7 pc)
    homolog to rattus Jtb (87 pc)
    homolog to murine Jtb (85.6 pc)
    Homologene
    FAMILY
  • JTB family
  • CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm,cytoskeleton
    text
  • intracellular membrane-bounded organelle
  • single-pass type I membrane protein
  • basic FUNCTION unknown
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS