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FLASH GENE
Symbol GPR75 contributors: npt/ - updated : 07-04-2006
HGNC name G protein-coupled receptor 75
HGNC id 4526
Location 2p16      Physical location : 54.080.049 - 54.087.126
Synonym symbol(s) GPR57, GPR-chr2, WI-31133
DNA
TYPE functioning gene
STRUCTURE 7.02 kb     2 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Map pter - D2S119 - D2S2291 - D2S2182 - D2S123 - D2S2251 - RPS27A - D2S378 - D2S393 - D2S337 - cen
Authors GeneMap (98)
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
2 - 2115 59.2 540 - -
EXPRESSION
Type restricted
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrain    
 spinal cord    
Visualeyeretina   
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelial    
Nervouscentral   
cells
SystemCellPubmedSpeciesStageRna symbol
Visualganglion cell
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • seven transmembrane spanning regions
  • HOMOLOGY
    interspecies homolog to C.elegans Y59H11AL.1
    Homologene
    FAMILY
  • G-protein coupled receptor 1 family
  • CATEGORY receptor membrane G
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION unknown
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS nervous system
    text vision
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility to age related macular degeneration
    Variant & Polymorphism other
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS