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FLASH GENE
Symbol ZNF124 contributors: npt - updated : 21-12-2009
HGNC name zinc finger protein 124
HGNC id 12907
Location 1q44      Physical location : 247.319.202 - 247.335.318
Synonym name
  • zinc finger protein from a hepatoblastoma cell line
  • zinc finger protein 124 (HZF-16)
  • Synonym symbol(s) HZF16, ZK7, HZF-16, MGC117046
    DNA
    TYPE functioning gene
    STRUCTURE 16.12 kb     4 Exon(s)
    Genomic sequence alignment details
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status confirmed
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - splicing 2080 - 296 - Miyake,Saleh
    also called HZF16
    4 - 1674 - 289 in hematopoietic progenitor cells, increased after VEGF stimulation Saleh
  • also called ZK7
  • may inhibit apoptotic cell death in HNSCC.
  • EXPRESSION
    Type widely
    constitutive of
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a Kruppel-associated box A-box domain at the NH2 terminus
  • seven ZNF motifs at the COOH terminus
  • conjugated MetalloP
    HOMOLOGY
    Homologene
    FAMILY
  • krueppel C2H2-type zinc-finger protein family
  • CATEGORY regulatory , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome
    basic FUNCTION
  • may be involved in the inhibitory effect of VEGF on apoptotic cell death in human hematopoietic cells
  • CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
  • Zn2+
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS