Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

Home Page

FLASH GENE

Symbol

ZNF124

contributors: npt - updated : 21-12-2009

HGNC name	zinc finger protein 124
HGNC id	12907

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	1q44      Physical location : 247.319.202 - 247.335.318
Synonym name	zinc finger protein from a hepatoblastoma cell line
	zinc finger protein 124 (HZF-16)
Synonym symbol(s)	HZF16, ZK7, HZF-16, MGC117046

DNA

TYPE	functioning gene
STRUCTURE	16.12 kb     4 Exon(s)

Genomic sequence alignment details
10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

confirmed

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed variant 2 - splicing 2080 isoform 2 - 296 - Miyake,Saleh also called HZF16 NM_003431 4 - 1674 NP_003422 - 289 in hematopoietic progenitor cells, increased after VEGF stimulation Saleh also called ZK7 may inhibit apoptotic cell death in HNSCC.

EXPRESSION

Type

widely

constitutive of

expressed in	(based on citations)
organ(s)

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	a Kruppel-associated box A-box domain at the NH2 terminus
	seven ZNF motifs at the COOH terminus

conjugated

MetalloP

HOMOLOGY

Homologene

FAMILY

krueppel C2H2-type zinc-finger protein family

CATEGORY

regulatory , transcription factor

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,nucleus,chromatin/chromosome

basic FUNCTION

may be involved in the inhibitory effect of VEGF on apoptotic cell death in human hematopoietic cells

CELLULAR PROCESS

nucleotide, transcription, regulation

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

binding

RNA

small molecule	metal binding,
	Zn2+

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS