basic FUNCTION
| involved in epithelial aminoacid (re)absorption, broad scope neutral aminoacids transporter |
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contribute to the renal reabsorption of neutral amino acids in the basolateral domain of epithelial proximal tubule cells (Park 2005) |
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play essential roles in the reabsorption of neutral amino acids from the epithelial cells to the blood stream in the kidney (Park 2005) |
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with SLC7A5, functions as influx and/or efflux transport machinery displaying a greater propensity for the outward transport of large and small neutral amino acids (Omidi 2008) |
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may be important to modulate thyroid hormone effects on osteoblast differentiation and on bone development and metabolism (Capelo 2009) |