Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | RGS9 | contributors: mct/npt - updated : 09-03-2016 |
HGNC name | regulator of G-protein signalling 9 |
HGNC id | 10004 |
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Corresponding disease |
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Location | 17q24.1 Physical location : 63.133.455 - 63.223.819 | ||
Synonym name | |||
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Synonym symbol(s) | RGS9L, MGC111763, MGC26458, PERRS |
DNA |
TYPE | functioning gene |
STRUCTURE | 90.27 kb 19 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | N | status | confirmed |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||
organ(s) |
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tissue |
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cells |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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mono polymer | heteromer , dimer |
HOMOLOGY |
interspecies | homolog to C.elegans EGL-10 |
homolog to yeast SST2 | |
homolog to C.elegans c16c2.2 | |
homolog to murine Rgs9 |
Homologene |
FAMILY |
CATEGORY | regulatory |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm | |
intracellular,nucleus | |
text | outer segments |
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling | sensory transduction/vision |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein | |
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cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) | PERRS |
Susceptibility | to antipsychotic-induced tardive dyskinesia in schizophrenia |
Variant & Polymorphism other | a significant association of the AGG haplotype (rs8077696-rs8070231-rs2292593) with antipsychotic-induced tardive dyskinesia in schizophrenia (Liou 2009) |
Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |
expression diminished in the amphetamine-treated animal model of schizophrenia and in post-mortem schizophrenia brain |