Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol AKAP4 contributors: mct/npt - updated : 03-09-2008
HGNC name a kinase (PRKA) anchor protein 4
HGNC id 374
Location Xp11.2      Physical location : 49.955.410 - 49.965.664
Synonym name
  • major sperm fibrous sheath protein
  • protein kinase A-anchoring protein 4
  • A-kinase anchor protein 82 kDa
  • testis-specific gene HI
  • Synonym symbol(s) AKAP82, Fsc1, p82, PRKA4, HI
    DNA
    TYPE functioning gene
    STRUCTURE 10.00 kb     6 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    6 - 2881 94 854 - Moretti (2007)
    6 - 2867 - 845 - Moretti (2007)
    EXPRESSION
    Type restricted
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Reproductivemale systemtestis   
    cell lineage
    cell lines
    fluid/secretion sperm
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    secondary structure an amphipathic helix binding domain
    HOMOLOGY
    Homologene
    FAMILY
  • AKAP110 family
  • CATEGORY chaperone/stress
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytoskeleton,microtubule
    text sperm fibrous sheath
    basic FUNCTION
  • a kinase (PRKA regulatory subunit RIIA) anchor protein tethering the enzyme near its physiological substrate(s), involved in sperm-motility
  • CELLULAR PROCESS cell organization/biogenesis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS