basic FUNCTION
| serine/threonine and tyrosine kinase, phosphorylating histone H2B |
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putatively involved in cell growth and development |
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could be novel and essential regulatory molecules for the regulation of cell fate including apoptosis |
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having an unexpected role as a scaffold for an E3 ubiquitin ligase complex, its kinase activity is required for the phosphorylation and subsequent degradation of the substrate, katanin p60 |
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presumed to be involved in regulating key developmental and cellular processes such as neurogenesis, cell proliferation, cytokinesis, and cellular differentiation |
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has unexpected role as a scaffold for an E3 ubiquitin ligase complex |
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involved in the response to DNA damage through TP53 phosphorylation |
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DYRK1A, DYRK2, and DYRK4 phosphorylate distinct although overlapping sets of the 720 different peptides in the phosphosite array |
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zinc finger transcriptional repressor, and an important regulator of epithelial-mesenchymal transition (EMT) |
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is a novel negative regulator of cardiomyocyte growth |
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expression is associated with lymph node involvement and is a possible predictive factor of breast cancer recurrence |
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DYRK2 down-regulates key molecules on cell cycle control and has functions during cell division |
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DYRK2 controls neddylation and is necessary for maintaining genome stability |