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FLASH GENE
Symbol ENTPD4 contributors: - updated : 05-04-2006
HGNC name ectonucleoside triphosphate diphosphohydrolase 4
HGNC id 14573
Location 8p22-p21.3      Physical location : 23.289.571 - 23.315.244
Synonym name
  • cDNA sequence,expressed in brain,64kDa,related to C elegans cosmid R07E4
  • apyrase lysosomal
  • lysosomal apyrase-like 1
  • Synonym symbol(s) KIAA0392, LAP70, LALP70, NTPDase-4, UDPase, LYSAL1
    EC.number 3.6.1.6
    DNA
    TYPE functioning gene
    STRUCTURE 30.00 kb     14 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Nervousbrain    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Epithelial    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • four apyrase domains
  • scavenger receptor cysteine-rich domain
  • HOMOLOGY
    interspecies homolog to C.elegans cosmid R07E4
    homolog to murine Lysal1
    Homologene
    FAMILY GDA1/CD39 (nucleoside phosphatase) family
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,lysosome
    text type 3 lysosomal/autophagic vacuole membrane
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    nucleobase, nucleoside, nucleotide and nucleic acid metabolism
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS