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FLASH GENE
Symbol CREBL2 contributors: npt/mct - updated : 20/11/2008
HGNC name cAMP responsive element binding protein-like 2
HGNC id 2350
Location 12p13.2-p13.1      Physical location : 12.764.830 - 12.798.041
Synonym symbol(s) MGC117311, MGC138362
DNA
TYPE like-sequence
STRUCTURE 33.21 kb     4 Exon(s)
10 Kb 5' upstream gene genomic sequence study
motif
MAPPING cloned Y linked   status provisional
Map pter - ETV6 - D12S358 - CREBL2 - CDKN1B - cen
Authors Hoornaert (98)
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
4 - 3748 13 120 - Hoornaert (1998)
EXPRESSION
Type ubiquitous
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver   highly
Endocrineadrenal gland   highly
 neuroendocrinepituitary  highly
Hearing/Equilibriumear   highly
Reproductivemale systemtestis  highly
Urinarykidney   highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / Hematopoieticbone marrow   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES fibrous
STRUCTURE
motifs/domains
  • a basic leucine-zipper (bZIP) domain
  • a DNA binding domain, rich in basic residues
  • a leucine zipper involved in protein dimerization
  • HOMOLOGY
    Homologene
    FAMILY
  • bZIP family
  • ATF subfamily
  • CATEGORY regulatory , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • acting as a suppressor of tumor
  • CELLULAR PROCESS nucleotide, transcription
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS