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FLASH GENE
Symbol GSTA2 contributors: - updated : 11-02-2004
HGNC name glutathione S-transferase A2
HGNC id 4627
Location 6p12.2      Physical location : 52.614.887 - 52.628.361
Synonym symbol(s) GST2
EC.number 2.5.1.18
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
STRUCTURE 13.00 kb     7 Exon(s)    multiples  Copie(s)
10 Kb 5' upstream gene genomic sequence study
text structure a proximal promoter essential for the binding of activating transcription factor complexes
MAPPING cloned Y linked   status provisional
Map cen - ICK - GSTA@ - qter
Authors Morel et al.(02)
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver    
Respiratorylung    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / Hematopoietic    
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
mono polymer homomer , heteromer , dimer
HOMOLOGY
interspecies homolog to murine Gsta2
homolog to C.elegans y32g9a.m
Homologene
FAMILY
  • GST superfamily
  • ALPHA family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • conjugating reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component dimer of A1 and A2
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS