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FLASH GENE
Symbol PTPRU contributors: - updated : 27-09-2004
HGNC name protein tyrosine phosphatase, receptor type, U
HGNC id 9683
Location 1pter-p35      Physical location : 29.563.027 - 29.653.325
Synonym name
  • protein tyrosine phosphatase,162kDa,receptor type
  • protein tyrosine phosphatase J
  • pancreatic carcinoma phosphatase 2
  • protein tyrosine phosphatase receptor omicron
  • Synonym symbol(s) PTPRU2, PTPRO2, hPTP-J, PCP-2, FMI, PTP, PTPPSI, PTPU2, GLEPP1, FLJ37530
    EC.number 3.1.3.48
    DNA
    TYPE functioning gene
    STRUCTURE 90.00 kb     31 Exon(s)
    Genomic sequence alignment details
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked   status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - - 5579 161 1436 - Yan
    - - 5597 - 1442 - Yan
    - - 5609 162 1446 - Yan
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Nervousbrain   highly
    Reproductivefemale systemovary  highly
     male systemtestis  highly
     male systemprostate  highly
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Muscularstriatumskeletal  
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a MAM domain, an Ig-like region,
  • four fibronectin FN III repeats
  • a transmembrane segment
  • two phosphatase domains with a large extracellular motif
  • conjugated GlycoP
    HOMOLOGY
    interspecies ortholog to murine Ptpru (89 pc)
    Homologene
    FAMILY PTPR family
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     plasma membrane
    text type I membrane protein
    basic FUNCTION tyrosine phosphatase, receptor
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS