basic FUNCTION
| putative ATP-dependent RNA helicase |
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essential for maintenance of functional mitochondria |
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playing an essential role for maintaining proper |
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mitochondrial function, likely through a conserved role in mitochondrial RNA regulation |
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may exert a role in mtDNA replication |
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important for the maintenance of the skin barrier |
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suppress apoptotic death and sister chromatid exchange, and impair mitochondrial RNA metabolism and protein synthesis |
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co-purifies with PNPase, and this may suggest participation of both proteins in mtRNA metabolism |
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major player in mitochondrial RNA surveillance and decay, but its physiological role might go beyond this functional niche |
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physical and functional interactions with known RecQ helicase-associated proteins strengthen the hypothesis that it may play a significant role in nuclear DNA metabolism as well |
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direct role of SUV3 in maintaining mitochondrial genome stability that is independent of intron turnover but requires the intact ATPase activity and the CC conserved region |
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participates potentially in the maintenance of mitochondrial genomic stability that is separable from its involvement in RNA degradation and processing |
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harbors a distinct function that requires both ATPase activity and C-terminal conserved region for regulating mtDNA replication and maintaining mitochondrial genomic stability that is independent of its involvement in intron turnover |
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helicase that is involved in efficient turnover and surveillance of RNA in eukaryotes |
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is also indispensable for mitochondrial RNA decay but its ribonucleolytic partner has so far escaped identification |