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FLASH GENE
Symbol HIST1H2BO contributors: - updated : 12-02-2004
HGNC name histone 1, H2bo
HGNC id 4758
Location 6p21.3      Physical location : 27.861.202 - 27.861.669
Synonym name H2B histone family, member N
Synonym symbol(s) H2B.2,H2B/n,H2BFN,dJ193B12.2
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
text N distal cluster
STRUCTURE 0.00 kb     1 Exon(s)
regulatory sequence Promoter (CAAT box) (TATA box)
text structure two TATA boxes, four CAAT boxes and one H2B box ona 313bp intergene promoter region (H2A.1/H2B.2)
MAPPING cloned Y linked Y status confirmed
regionally located member of the small cluster of 16 histone genes located 2Mb centromeric to the major cluster of 35 histone genes
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES basic
STRUCTURE
motifs/domains
mono polymer heteromer , octamer
HOMOLOGY
interspecies homolog to C.elegans B0035.8
Homologene
FAMILY H2B histone family
CATEGORY DNA associated , transcription factor
SUBCELLULAR LOCALIZATION     intracellular
intracellular,nucleus,chromatin/chromosome,nucleosome
basic FUNCTION
  • playing a role in the compaction of DNA into nucleosomes
  • CELLULAR PROCESS nucleotide, chromatin organization, remodeling
    nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component component of nucleosomes
    INTERACTION
    DNA approximatively 0.146 kb
    RNA
    small molecule
    protein
  • H2A
  • H2B
  • H3
  • H4
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS