basic FUNCTION
| upon ligand stimulation (acetate), mediates intracellular calcium mobilization |
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involved with acetate and propionate short chain fatty acids in adipogenesis |
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a role in the recruitment of polymorphonuclear cells |
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may have a role in the recruitment of leukocytes populations toward sites of bacterial infection |
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mediate short-chain fatty acids signaling in mammary epithelial cells and thereby play an important role in their stress management |
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FFAR2 binding of short-chain fatty acids potentially provides a molecular link between diet, gastrointestinal bacterial metabolism, and immune and inflammatory responses |
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G protein-coupled receptor activated by short chain carboxylic acids |
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bipotential role of polymorphonuclear leukocytes in mediating tissue destruction in chronic intestinal inflammation |
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G-protein-coupled receptor for short-chain fatty acids |
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functions as a tumor suppressor by mediating short-chain fatty acids -induced cell proliferation inhibition and apoptotic cell death in colon cancer |
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FFAR2, FFAR4 have different roles in mediating metabolic function in a number of tissues in the human body |
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play important roles not only as essential nutritional components but also as signaling molecules in numerous physiological processes |