basic FUNCTION
| may be linking the cornified envelope to desmosomes and intermediate filaments |
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can function in relocating protein kinase B into various cell compartments |
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component of desmosomes and the epidermal cornified envelope |
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first protein described to modify the capacity of the melanin-concentrating hormone-1 receptor to initiate signal transduction |
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cytoskeletal linker protein that participates in the assembly of epidermal cell cornified envelope and regulates keratin organisation in simple epithelial cells |
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with Involucrin, and EVPL, form the protein scaffold on which the cornified envelope assembles |
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arterial intima-enriched (AIE) gene, with periplakin, SPRR3, envoplakin, galectin 7, and plakoglobin that are functionally related in that they contribute to the stress properties of stratified epithelium |