Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | PFKFB3 | contributors: mct/npt - updated : 07-06-2016 |
HGNC name | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
HGNC id | 8874 |
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Location | 10p15.1 Physical location : 6.186.842 - 6.277.505 |
Synonym name | |
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Synonym symbol(s) | IPFK2, PFK2, PFK-2, FLJ37326 |
EC.number | 2.7.1.105, 3.1.3.46 |
DNA |
TYPE | functioning gene |
STRUCTURE | 90.67 kb 15 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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regulatory sequence | Promoter (TATA box) |
cytosine-phosphate-guanine/HTF | |
Binding site | |
text structure | |
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MAPPING | cloned | Y | linked | N | status | provisional |
RNA |
TRANSCRIPTS | type | messenger |
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text | spliced into several variants that encode distinct carboxyl-terminal domains (Yalcin 2009) |
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EXPRESSION |
Type | ubiquitous |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
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tissue |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
physiological period | embryo, fetal, pregnancy |
Text | placenta, embryonic tissue, umbilical cord |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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HOMOLOGY |
interspecies | homolog to rattus Pfkfb3 (97.64 pc) |
homolog to murine Pfkfb3 (97.69 pc) |
Homologene |
FAMILY |
CATEGORY | enzyme |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm | |
intracellular,nucleus | |
text | localized to the nucleus (Yalcin 2009) |