Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol AK3 contributors: - updated : 16-10-2007
HGNC name adenylate kinase 3
HGNC id 17376
Location 9p24.3-p24.1      Physical location : 4.711.157 - 4.741.227
Synonym name
  • GTP-AMP phosphotransferase
  • adenylate kinase-3, mitochondrial
  • adenylate kinase 6
  • adenylate kinase 3 like 1
  • Synonym symbol(s) KAD3, EVI143, RP11-6J24.4, AK3L1, AK6, AKL3L, AKL3L1, FIX
    EC.number 2.7.4.10
    DNA
    TYPE functioning gene
    STRUCTURE 30.00 kb     5 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    text structure intronless
    MAPPING cloned Y linked N status confirmed
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type ubiquitous
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart   highly
    Digestiveliver   highly
    Endocrineadrenal gland   highly
     parathyroid   highly
    Urinarykidney   moderately
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Muscularstriatumskeletal  
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    mono polymer monomer
    HOMOLOGY
    interspecies homolog to murine Ak3
    Homologene
    FAMILY adenylate kinase family
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria,matrix
    basic FUNCTION
  • adenylate kinase 3 implicated in adenine and guanine nucleotide pool homeostasis
  • regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS