Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | C8G | contributors: mct - updated : 11-01-2012 |
HGNC name | complement component 8, gamma polypeptide |
HGNC id | 1354 |
|
Location | 9q34.3 Physical location : 139.839.697 - 139.841.426 |
Genatlas name | complement component 8,gamma-1 globulin,subunit of the membrane attack complex |
Synonym symbol(s) | C8C, MGC142186 |
DNA |
TYPE | functioning gene |
STRUCTURE | 1.73 kb 7 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
---|
MAPPING | cloned | Y | linked | status | confirmed |
RNA |
TRANSCRIPTS | type | messenger |
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|
EXPRESSION |
Type | restricted |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||
organ(s) |
|
cell lineage
cell lines
| fluid/secretion
| plasma | |
at STAGE |
PROTEIN |
PHYSICAL PROPERTIES | Hydrophobic | |
STRUCTURE |
motifs/domains
|
secondary structure | comprising a single eight-stranded continuously hydrogen-bounded antiparallel beta-barrel which encloses an internal ligand binding site |
mono polymer | heteromer , dimer |
HOMOLOGY |
interspecies | homolog to murine C8g |
Homologene |
FAMILY | lipocalin family (kernel group) of small secreted protein |
CATEGORY | immunity/defense |
SUBCELLULAR LOCALIZATION | extracellular |
plasma membrane |