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FLASH GENE
Symbol PAPPA contributors: mct - updated : 23-09-2013
HGNC name pregnancy-associated plasma protein A, pappalysin 1
HGNC id 8602
Location 9q33.2      Physical location : 118.916.070 - 119.164.599
Synonym name
  • insulin-like growth factor-dependent IGF-binding protein 4 protease
  • differentially expressed in placenta 1
  • aspecific BCL2 ARE-binding protein 2
    • Synonym symbol(s) PAPA, DIPLA1, PAPP-A, PAPPA1, ASBABP2, IGFBP-4ase, ASBABP2
    EC.number 3.4.24.79
    DNA
    TYPE functioning gene
    SPECIAL FEATURE opposite orientation
    text
  • in opposite orientation with DIPAS
    • STRUCTURE 248.53 kb     22 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked   status confirmed
    Map cen - F36 - C9orf27 - PAPPA - qter
    Authors Daigo (99)
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    22 - 11025 - 1627 - 2007 1709704
    EXPRESSION
    Type widely
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularvessel   highly
    Reproductivefemale systembreast   
     female systemovary   
     female systemuterus  moderately
     female systemplacenta  predominantly Homo sapiensAdult
    Urinarykidney    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Connectiveadipose  moderately
    Epithelialbarrier/liningendometrium  
    Muscularsmouthuterusmyometrium 
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period pregnancy
    Text placenta, chorionic villi
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains

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