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FLASH GENE
Symbol GGT7 contributors: mct - updated : 26-05-2008
HGNC name gamma-glutamyltransferase 7
HGNC id 4259
Location 20q11.22      Physical location : 33.432.523 - 33.460.661
Synonym name
  • gamma-glutamyltransferase-like 3
  • gamma-glutamyltransferase 4
  • gamma-glutamyltransferase-like 5
  • gamma-glutamyltranspeptidase-like 3
  • Synonym symbol(s) GGT2L3, GGTL5, D20S101, dJ18C9.2, GGTL3, GGT4
    EC.number 2.3.2.2
    DNA
    TYPE functioning gene
    STRUCTURE 28.00 kb     15 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    15 - 2640 - 662 - He, Heisterkamp (2008)
    - - 1514 - 251 - He
    - - 2772 - 609 - He
    EXPRESSION
    Type widely
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Lymphoid/Immunespleen    
    Nervousbrain    
    Reproductivefemale systemovary  highly
    Respiratoryrespiratory tractlarynx  highly
    Urinarykidney    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Connectiveadipose  highly
    cell lineage
    cell lines
    fluid/secretion blood
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY GGT family
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
    basic FUNCTION
  • playing a key role in the gamma-glutamyl cycle, a pathway for the synthesis and degradation of glutathione
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein interacting with SLC3A2 and FAM57A
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS