basic FUNCTION
| protects neurons by binding to a complex or complexes involving CNTFR/IL27RA/IL6ST |
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inhibits neuronal cell death and dysfunction by binding to a novel IL6-receptor-related receptor(s) on the cell surface involving CNTFR, IL27RA, and IL6ST |
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has antiapoptotic properties, and may play an important role in preventing apoptosis in sperm and testis |
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may play a role and may have a protective effect in early atherosclerosis |
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plays a protective role through its antiapoptotic activity that interferes with BAX activation, which suppresses Bax-dependent apoptosis |
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suppress the JUN N-terminal kinase (JNK) and ASK/JNK-mediated neuronal cell death |
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may also protect against cognitive impairment due to ischemia/reperfusion injury |
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bioactive peptide that is likely to inhibit both neuronal death and dysfunction only related to Alzheimer disease (AD) by binding to a Humanin receptor on the cell-surface and by activating a STAT3-mediated signal, preventing the onset of dementia |
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displaying a protective activity against a range of cytotoxic and neurotoxic insults |
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protects cortical neurons from hypoxia/reperfusion (I/R) injury by the increased SOD1 activity and the protective effect of MTRNR2L1 on neurons against I/R is concentration-dependent |
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is a secreted bioactive peptide that suppresses cell toxicity caused by a variety of insults |
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short bioactive peptide, inhibiting a variety of cell deaths |
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binds to IGFBP3 and regulates its interaction with KPNB1 |
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protected RPE cells from oxidative stress-induced cell death by STAT3 phosphorylation and inhibiting CASP3 activation |