basic FUNCTION
| MZT1, MZT2A, MZT2B copurified with subunits of the gamma-tubulin ring complex (gamma-TuRC), which is essential for spindle assembly and chromosome segregation |
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plays a unique role within the TUBG1 components in attachment of this complex to the major microtubule organizing centers (MTOCs) site |
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plays an essential role in mitotic spindle formation as a component of the Gamma-tubulin ring complex |
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MST1 contributes to the microtubule-organizing centers (MTOCs) function through regulation of TUBGCP3 |
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MZT1 is a 'priming factor' for gamma-tubulin ring complex (GTuRC) that allows spatial regulation of nucleation |