basic FUNCTION
| its function involves forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the nuclear pore complexes in the membrane. |
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transmembrane nucleoporin required for NPC assembly and nucleocytoplasmic transport |
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is a nuclear membrane protein comprising the nuclear pore complex, and likely the nuclear pore complex plays an important role in mammalian gametogenesis and skeletal development |
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NDC1 is a major nuclear pore protein, and is critical for nuclear pore complex assembly and nuclear morphology maintenance in mammalian cells |
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after spindle pole body (SPB) insertion, membrane-associated proteins including the conserved NDC1 encircle the SPB and retain it within the nuclear envelope (NE) |