basic FUNCTION
| acting as a transcriptional repressor of GATA factor function |
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critical nuclear repressor in somatic cells of the gonad that is required for germ cell development |
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critical nuclear repressor in somatic cells of the gonad that is required for germ cell development, suggesting the importance of somatic-germ cell interactions in the regulation of this critical process |
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somatic cell protein ZGLP1 is not necessary for many pregranulosa cell functions but is required for germ cell survival |
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ZGLP1 is a regulator of adipogenesis, which could be an alternate pathway leading to improved lipid homeostasis and controlled downstream insulin signaling |
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acts downstream of bone morphogenetic protein, but not retinoic acid (RA), and is essential for the oogenic program and meiotic entry |