Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | LRTOMT | contributors: npt - updated : 27-10-2008 |
HGNC name | leucine rich transmembrane and 0-methyltransferase domain containing |
HGNC id | 25033 |
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Corresponding disease |
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Location | 11q13.4 Physical location : 71.791.381 - 71.821.827 | ||
Synonym name | |||
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Synonym symbol(s) | COMT2, LRRC51, LRTOMT1, LRTOMT2, FLJ52451, TOMT | ||
EC.number | 2.1.1.6 |
DNA |
TYPE | functioning gene |
STRUCTURE | 30.45 kb 9 Exon(s) |
MAPPING | cloned | Y | linked | N | status | provisional |
RNA |
TRANSCRIPTS | type | messenger |
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text | using a set of different exons and alternative reading frames (Schulze 2009) ; variants 4 and 5 encode the same protein |
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EXPRESSION |
Type |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||
organ(s) |
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cells |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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HOMOLOGY |
interspecies | homolog to murine Comt2 (92.64p100) |
Homologene |
FAMILY | |
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CATEGORY | enzyme , signaling neurotransmitter |
SUBCELLULAR LOCALIZATION |
basic FUNCTION | |
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CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling | neurotransmission , sensory transduction/hearing |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein |
cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) | DFNB63 |
Susceptibility |
Variant & Polymorphism
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |