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FLASH GENE
Symbol TAF1D contributors: mct - updated : 27-06-2013
HGNC name TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa
HGNC id 28759
Location 11q21      Physical location : 93.469.095 - 93.474.703
Synonym name
  • Josephin domain containing 3
  • Synonym symbol(s) MGC5306, JOSD3, TAFI41, TAF(I)41
    DNA
    TYPE functioning gene
    STRUCTURE 5.61 kb     6 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    6 - 1321 - 278 - 2004 15520167
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines carcinomas and tumor cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY
    CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,nucleolus
    text
  • resides at the rDNA promoter in the nucleolus
  • basic FUNCTION
  • may be involved in repair pathway
  • component of SL1 (RNA polymerase I transcription), which functions in Pol I transcription
  • integral to transcriptionally active TAF1A, TAF1B and imply a role for TAF1A, TAF1B, including the TAF1D subunit, in Pol I recruitment and, therefore, preinitiation complex formation
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS