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FLASH GENE
Symbol CSDC2 contributors: mct/npt - updated : 10-10-2009
HGNC name cold shock domain containing C2, RNA binding
HGNC id 30359
Location 22q13.2      Physical location : 41.957.013 - 41.972.670
Synonym name RNA-binding protein PIPPin
Synonym symbol(s) PIPPIN, dJ347H13.2
DNA
TYPE functioning gene
STRUCTURE 15.66 kb     4 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
4 - 2545 - 153 - Raimondi (2003)
EXPRESSION
Type restricted
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrain   highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • N-terminal RNA-binding region with all of the phosphorylation sites
  • RNA-binding motifs that flank a central cold shock domain (Lee 2009)
  • HOMOLOGY
    intraspecies paralog to CARHSP2
    Homologene
    FAMILY
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,Golgi
    intracellular,nucleus
    text
  • a subset found in the nucleus may play a role during early stages of mRNA synthesis within chromatin structures (Lee 2009)
  • basic FUNCTION
  • involved in decidualization during normal pregnancy (Vallejo 2009)
  • bind and inhibit the translation of specific histone mRNAs (Lee 2009)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA binding
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS