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FLASH GENE
Symbol FAM109B contributors: mct - updated : 18-10-2011
HGNC name family with sequence similarity 109, member B
HGNC id 27161
Location 22q13.2      Physical location : 42.470.254 - 42.475.441
Synonym name
  • sesquipedalian 2
  • NADH ubiquinone oxidoreductase (Q reductase), component beta 14
  • inositol polyphosphate phosphatase interacting protein of 27 kDa (IPIP27)B
  • Synonym symbol(s) DKFZp686J07229, NDUFB14, IPIP27B, SES2, MGC125831, MGC125832
    DNA
    TYPE functioning gene
    STRUCTURE 5.19 kb     3 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    3 - 2369 - 259 - 2010 20133602
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    mono polymer homomer , heteromer , dimer
    HOMOLOGY
    Homologene
    FAMILY
    CATEGORY
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,Golgi
    intracellular,cytoplasm,organelle,endosome
    text localize to early and recycling endosomes and the trans-Golgi network (TGN)
    basic FUNCTION
  • key player in endocytic trafficking
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • form homo- and heterodimers
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interact with the ASH-RhoGAP-like (ASPM-SPD-2-Hydin homology and Rho-GTPase Activating Domain-like) domain of OCRL
  • OCRL-binding protein, that also bind the related 5-phosphatase INPP5B
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS