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FLASH GENE
Symbol C11orf54 contributors: SGE/NPT - updated : 04-02-2010
HGNC name chromosome 11 open reading frame 54
HGNC id 30204
Location 11q21      Physical location : 93.474.792 - 93.496.246
Synonym name
  • PTD012 protein
  • hypothetical protein LOC28970
  • Synonym symbol(s) PTD012, LP4947
    EC.number 3.1.-.-
    DNA
    TYPE functioning gene
    STRUCTURE 21.46 kb     8 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    8 - 2403 - 265 - -
    EXPRESSION
    Type widely
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveintestinesmall intestine  moderately
     liver   moderately
    Lymphoid/Immunelymph node   moderately
    Reproductivemale systemtestis  moderately
    Urinarykidney   predominantly
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Blood / hematopoieticbone marrow   
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    secondary structure alphabetabetaalpha four-layer topology (Manjasetty 2006)
    HOMOLOGY
    Homologene
    FAMILY
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • exhibits ester hydrolase activity on the substrate p-nitrophenyl acetate (Manjasetty 2006)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
  • ions Zn2+
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS