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FLASH GENE
Symbol OLFML1 contributors: mct/npt - updated : 08/11/2008
HGNC name olfactomedin-like 1
HGNC id 24473
Location 11p15.4      Physical location : 7.506.599 - 7.532.604
Synonym symbol(s) UNQ564, MVAL564
DNA
TYPE functioning gene
STRUCTURE 25.81 kb     3 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
3 - 2719 45.8 402 - Clark (2003)
EXPRESSION
Type widely
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   highly
Digestiveintestinesmall intestine  lowly
 liver   moderately
Lymphoid/Immunespleen   highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • an olfectamine domain in its C-terminus
  • conjugated GlycoP
    HOMOLOGY
    interspecies ortholog to murine Olfml1
    Homologene
    FAMILY
  • olfactomedin-like family
  • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION extracellular
    basic FUNCTION
  • playing an important role in regulating the production of neural crest cells by the neural tube
  • may play a significant role in the regulation of cell proliferation
  • exhibits the promotion of cell proliferation, along with the increase of percentage of S phase cells
  • may be involved in the self-renewal and regeneration of small intestine villous epithelium
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS