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FLASH GENE
Symbol ZNF655 contributors: - updated : 17-06-2005
HGNC name zinc finger protein 655
HGNC id 30899
Location 7q22.1      Physical location : 99.156.044 - 99.174.074
Synonym name Vav-interacting Kruppel-like protein
Synonym symbol(s) FLJ23461, VIK, VIK-1
DNA
TYPE functioning gene
STRUCTURE 17.00 kb     7 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- splicing 4758 57.4 491 - Houlard
  • encodong the same isoform a than variant 3
  • - splicing 1608 20 181 - Houlard
  • including alternate exons in the 3' coding region and 3' UTR, compared to variant 1
  • encoding isoform b
  • - splicing 4585 57.4 491 - Houlard
  • having an alternate 5' exon
  • encoding the same isoform a than variant 1
  • - splicing 1222 12 110 - Houlard
  • having an alternate 5' exon and an alternate 3' exon compared to variant 1
  • encoding the isoform c
  • - splicing 2002 8.3 76 - Houlard
  • including alternate exons in the 3' coding region and 3' UTR compared to variant 1
  • encoding the isoform d
  • - splicing 4983 - 46 - Houlard
  • encoding the shortest isoform e
  • having two additional internal exons compared to variant 1, which result in an immediate translation termination
  • EXPRESSION
    Type widely
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestivemouthtongue  moderately
     pancreas exocrine   moderately
     stomach   highly
    Lymphoid/Immunethymus   highly
    Reproductivemale systemtestis  highly
    Respiratorylung   highly
     respiratory tractlarynx  moderately
    Skin/Tegumentskin   moderately
    Urinarybladder   moderately
     kidney   moderately
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Muscular    
    cell lineage
    cell lines
    fluid/secretion blood
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • six C2H2-type zinc fingers
  • HOMOLOGY
    interspecies ortholog to murine Zfp655
    Homologene
    FAMILY
  • krueppel C2H2-type zinc-finger protein family
  • CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • may function as a transcription factor
  • CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
  • Zn2+
  • protein
  • VAV1
  • CDK4
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS