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FLASH GENE
Symbol DCP1B contributors: mct/npt - updated : 26-04-2005
HGNC name DCP1 decapping enzyme homolog B (S. cerevisiae)
HGNC id 24451
Location 12p13.33      Physical location : 2.055.213 - 2.113.677
Synonym name decapping enzyme Dcp1b
Synonym symbol(s) FLJ31638
EC.number 3.-.-.-
DNA
TYPE functioning gene
STRUCTURE 58.46 kb     9 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
9 - 2105 67.6 617 - -
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivemale systemtestis   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a poly-gln domain
  • HOMOLOGY
    Homologene
    FAMILY
  • DCP1 family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • may play a role in the degradation of mRNAs, both in normal turn-over and in nonsense-mediated mRNA decay
  • may be generating m7GDP and 5'-phosphorylated mRNAs
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA binding
    small molecule
    protein
  • binding DCP1A and DCP2
  • important subunits of PBs (processing bodies) and is activated on AU-rich element-mRNAs by the protein ZFP36
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS