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FLASH GENE
Symbol TRA2A contributors: npt - updated : 18-04-2005
Location 7p15.3      Physical location : 23.544.401 - 23.571.656
Genatlas name
  • transformer-2 alpha
  • putative MAPK activating protein PM24
  • Synonym symbol(s) HSU53209
    DNA
    TYPE functioning gene
    STRUCTURE 27.00 kb     8 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - splicing 1807 32 282 - Dauwalder
    - splicing - 12 113 - Dauwalder
    EXPRESSION
    Type ubiquitous
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart   highly
    Digestivemouthtongue  highly
     pancreas exocrine   predominantly
    Lymphoid/Immunelymph node   highly
     spleen   predominantly
     thymus   highly
    Respiratorylung   highly
     respiratory tractlarynx  highly
    cell lineage
    cell lines
    fluid/secretion blood
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a RNA recognition motif (RRM) domain
  • RS domains
  • conjugated PhosphoP
    HOMOLOGY
    Homologene
    FAMILY
  • splicing factor SR family
  • CATEGORY regulatory , RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • participating in the control of pre-mRNA splicing
  • CELLULAR PROCESS nucleotide, RNA splicing
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA sequence-specific RNA-binding (sequence containing GAA repeats)
    small molecule
    protein
  • A3 enhancer proteins SRp75, SRp55, SRp40 and SRp30
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS