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FLASH GENE
Symbol ERGIC1 contributors: mct - updated : 22-12-2015
HGNC name endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
HGNC id 29205
Location 5q35.1      Physical location : 172.261.222 - 172.379.683
Synonym name
  • endoplasmic reticulum-golgi intermediate compartment 32 kDa protein
  • ER-Golgi intermediate compartment 32 kDa protein
  • Synonym symbol(s) MGC14345, ERGIC32, KIAA1181, NET24
    DNA
    TYPE functioning gene
    STRUCTURE 118.47 kb     10 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    10 - 2949 - 290 - -
    EXPRESSION
    Type ubiquitous
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveintestinelarge intestinecolon highly
    Reproductivefemale systembreastmammary gland highly
     male systemprostate  predominantly
    Respiratorylung   moderately
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY
    CATEGORY transport
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,endoplasmic reticulum
    intracellular,cytoplasm,organelle,Golgi
    text
  • AIM1, ERGIC1 and TMED3 were co-expressed in the set of genes functionally annotated to ER and Golgi apparatus and redox reactions
  • basic FUNCTION
  • cycling membrane protein contributing to the membrane traffic and selective transport of cargo between the ER, the intermediate compartment, and the Golgi apparatus
  • high AIM1 and TMED3 expression associates with genes involved in lipid metabolism, and high ERGIC1 and TMED3 expression with genes involved in redox homeostasis
  • ERGIC1 and TMED3 expression associated with ER and Golgi apparatus function
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • SDBCAG84
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --over  
    in prostate cancer tissues
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS