basic FUNCTION
| involved in mitochondrial proliferation |
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serve as inducible coregulator of nuclear receptor in the control of cellular energy metabolic pathways ( |
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role in the integration of pathways directing mitochondrial respiratory function and cell growth central transcriptional coactivator that regulate cell metabolic processes ranging from mitochondrial biogenesis to oxidative respiration |
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general role for PRC in the adaptive response to cellular dysfunction |
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growth-regulated transcriptional cofactor known to activate many of the nuclear genes specifying mitochondrial respiratory function |
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is a negative regulator of endothelial inflammation |
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can inhibit adhesion molecule expression and monocyte attachment to activated endothelial cells |