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FLASH GENE
Symbol MAEA contributors: - updated : 28-02-2005
HGNC name macrophage erythroblast attacher
HGNC id 13731
Location 4p16.3      Physical location : 1.283.671 - 1.333.924
Synonym name erythroblast macrophage protein
Synonym symbol(s) EMP, HLC-10
DNA
TYPE functioning gene
STRUCTURE 50.00 kb     10 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver    
Nervousbrain    
Respiratorylung    
Urinarykidney    
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a small N-terminal domain
  • a single transmembrane domain
  • a large cytoplasmic domain containing several tyrosine residues that, when phosphorylated, could interact with protein recognition modules
  • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION extracellular
        plasma membrane
        intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • promoting terminal maturation and enucleation of erythroblasts, presumably by suppressing apoptosis
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS