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FLASH GENE
Symbol OTUD4 contributors: - updated : 26-03-2007
HGNC name OTU domain containing 4
HGNC id 24949
Location 4q31.21      Physical location : 146.054.802 - 146.100.832
Synonym name
  • HIV-1 induced protein HIN-1
  • OTU domain-containing protein 4
  • Synonym symbol(s) HIN1, KIAA1046, HSHIN1, DKFZp434I0721
    DNA
    TYPE functioning gene
    STRUCTURE 41.00 kb     20 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - - 6980 - 1048 - Krop
    - - 864 - 145 - Krop
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Lymphoid/Immunelymph node    
     thymus    
    Respiratorylung    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Connectiveadipose   
    Muscular    
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Reproductiveoocyte
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • one OTU domain
  • one tudor domain
  • HOMOLOGY
    interspecies ortholog to murine Otud4
    ortholog to rattus otud4
    Homologene
    FAMILY OTU-like cysteine protease family
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    intracellular,nucleus
    basic FUNCTION
  • playing an essential role for female fertility, germ cell division and differentiation
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    activated by OVOL1
    induced by by hiv-1 insertion
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS