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FLASH GENE
Symbol CLVS2 contributors: SGE/npt - updated : 11-12-2009
HGNC name clavesin 2
HGNC id 23046
Location 6q22.31      Physical location : 123.317.581 - 123.385.063
Synonym name
  • chromosome 6 open reading frame 212
  • chromosome 6 open reading frame 213
  • hypothetical protein LOC134829
  • retinaldehyde binding protein 1-like 2
  • Synonym symbol(s) bA160A4, C6orf212, c6orf213, MGC120572, RLBP1L2
    DNA
    TYPE functioning gene
    STRUCTURE 67.40 kb     6 Exon(s)
    MAPPING cloned Y linked   status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    6 - 2010 38 327 - -
    EXPRESSION
    Type restricted
       expressed in (based on citations)
    organ(s)
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Nervousneuron
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • one CRAL-TRIO domain
  • HOMOLOGY
    interspecies homolog to murine Rlbp1l2 (97.9pc)
    homolog to rattus Rlbp1l2 (98.8pc)
    Homologene
    FAMILY
  • clavesin family
  • CATEGORY transport
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,Golgi
    intracellular,cytoplasm,organelle,endosome
    intracellular,cytoplasm,cytosolic,vesicle
    text
  • clathrin-coated vesicles and trans-Golgi network
  • basic FUNCTION
  • may provide a unique neuron-specific regulation of late endodome/lysosome morphology (Katoh 2009)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • forming a complex with clathrin heavy chain and adaptor protein-1 on clathrin-coated vesicles
  • INTERACTION
    DNA
    RNA
    small molecule other,
  • lipid phosphatidylinositol 3,5-bisphosphate partner
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS