motifs/domains
| an N-terminal signal peptide |
|
a potential transmembrane domain |
|
one Trx-like domain with an unusual catalytic motif, SNDC instead of CXXC, and is therefore thought to be inactive in terms of oxidoreductase activity (Sugiura 2010) |
|
an Myb DNA-binding domain repeat signature |
|
an ER-targeting signal sequence, |
|
an endoplasmic reticulum (ER) membrane retention signal (KKXX-like motif) |
|
a dileucine motif in the tail |
SUBCELLULAR LOCALIZATION
| plasma membrane
|
| intracellular
|
| intracellular,cytoplasm,organelle,mitochondria
|
| intracellular,cytoplasm,organelle,endoplasmic reticulum
|
| intracellular,cytoplasm,cytoskeleton
|
| intracellular,nucleus
|
| intracellular,nuclear envelope,ext
|
text
| localizes to the ER mitochondria-associated membranes (MAMs) |
|
TMX2 localizes in the outer nuclear membrane with its N-terminus and C-terminus facing the cytoplasm |