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FLASH GENE
Symbol PDCD7 contributors: - updated : 16-12-2004
HGNC name programmed cell death 7
HGNC id 8767
Location 15q22.2      Physical location : 65.409.717 - 65.426.174
Synonym name apoptosis-related protein ES18
Synonym symbol(s) ES18, HES18, MGC22015
DNA
TYPE functioning gene
STRUCTURE 17.00 kb     5 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Lymphoid/Immunelymph node    
 thymus    
Reproductivemale systemtestis   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a proline-rich N terminus
  • acidic regions with high contents of glutamic acid
  • C-terminal half having several alpha-helix regions, evenly spaced leucines and hydrophobic amino acids
  • LxxLL transcriptional coactivator signature motif
  • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION involved in specific apoptotic processes in T-cells
    CELLULAR PROCESS cell life, cell death/apoptosis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS