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FLASH GENE
Symbol SLC41A2 contributors: mct - updated : 14-10-2011
HGNC name solute carrier family 41, member 2
HGNC id 31045
Location 12q23.3      Physical location : 105.197.275 - 105.322.472
Synonym name SLC41A1-like 1
Synonym symbol(s) SLC41A1-L1, MGC125330, MGC125331
DNA
TYPE functioning gene
STRUCTURE 125.20 kb     10 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
10 - 3548 - 573 - 2003 12810078
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver    
 stomach    
Lymphoid/Immunetonsils    
Reproductivefemale systembreastmammary gland  
Urinarykidney    
cell lineage
cell lines
fluid/secretion blood
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • an N-terminus-outside/C-terminus-inside 11-TM (transmembrane)-span topology
  • HOMOLOGY
    interspecies homolog to rattus LOC362861
    Homologene
    FAMILY solute carrier family
    CATEGORY transport carrier
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • having cation transporter activity
  • Mg2+ transporter that might be involved in magnesium homeostasis in epithelial cells
  • functions as a plasma-membrane Mg2+ transporter
  • its expression is effective in restoring the change in cell morphology, disruption of the cytoskeleton and directional cell motility caused by depletion of the channel-kinase (
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    Other regulated by magnesium
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS