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FLASH GENE
Symbol SPHKAP contributors: npt - updated : 02-09-2006
HGNC name SPHK1 interactor, AKAP domain containing
HGNC id 30619
Location 2q36      Physical location : 228.844.669 - 229.046.361
Synonym name
  • sphingosine kinase type 1-interacting protein
  • SPHK1 (sphingosine kinase type 1) interacting protein
  • a kinase anchor protein SPHKAP
  • Synonym symbol(s) KIAA1678, MGC132614, SKIP, SPHKIP, MGC132616, DKFZp781J171, DKFZp781H143
    DNA
    TYPE functioning gene
    STRUCTURE 201.00 kb     11 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    11 - 6824 - 1671 - -
    EXPRESSION
    Type restricted
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart    
    Nervousbrain    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Blood / hematopoieticbone marrow   
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period embryo
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    intraspecies homolog to AKAP1
    Homologene
    FAMILY
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • playing a regulatory role in the modulation of SPHK1 activity
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • binding SPHK1
  • cell & other
    REGULATION
    induced by TGF-beta
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS