basic FUNCTION
| peripheral protein of the inner membrane facing the intermembrane space |
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scaffolding protein that stabilizes protein complexes involved in maintaining crista architecture and protein import and is thus essential for maintaining mitochondrial structure and function |
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essential role in maintaining crista junctions architecture, crista morphology, and mitochondrial function |
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could be one of the key proteins that coordinate protein import and mitochondrial morphology, the two essential processes involved in proper functioning of mitochondria |
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integrating role of MINOS subunits (IMMT, MINOS1, and CHCHD3) in the structural organization of the organelle in mitochondria |
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CHCHD3 oxidation plays a role in MICOS assembly and the maintenance of the proper inner membrane morphology, but is not essential for its integration into the MICOS complex |
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is likely a redox-dependent regulator of MICOS function |