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FLASH GENE
Symbol MED16 contributors: mlc - updated : 19-12-2007
HGNC name mediator complex subunit 16
HGNC id 17556
Location 19p13.3      Physical location : 867.961 - 893.218
Synonym name
  • vitamin D receptor -interacting protein ,92-KD
  • thyroid hormone receptor associated protein 5
  • thyroid hormone receptor-associated protein, 95-kD subunit
  • Synonym symbol(s) DRIP92, TRAP95, THRAP5
    DNA
    TYPE functioning gene
    STRUCTURE 25.00 kb     16 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    16 - 2952 - 877 - Sato (2004)
    EXPRESSION
    Type widely
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestivesalivary gland   highly
    Endocrineparathyroid   highly
    Reproductivefemale systemovary  highly
    Visualeyelens   
     eyeanterior segmentiris  
     eyeuveachoroid  
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Epithelialbarrier/liningretinal pigment epithelium (RPE)  
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    a short leucine zipper near the N terminus
    HOMOLOGY
    Homologene
    FAMILY
    CATEGORY receptor nuclear
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • coactivator required for activation of RNA polymerase II transcription by DNA bound transcription factors
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS