basic FUNCTION
| potentially playing an important role in the development of the nascent mesoderm including primordial germ cells |
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playing a role in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm |
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definings the rostrocaudal patterning of the somites by participating in distinct Notch pathways |
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cooperative Mesp activity is required for normal somitogenesis along the anterior-posterior axis |
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has a significant role in the epithelialization of somitic mesoderm |
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a key factor sufficient to induce the formation of ectopic heart tissue in vertebrates and increase cardiovasculogenesis by ES cells |
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involved in cardiovascular differentiation through DKK1-mediated blockade of Wnt-signalling |
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acts as a key regulatory switch during cardiovascular specification, residing at the top of the hierarchy of the gene network responsible for cardiovascular cell-fate determination |
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coordinately regulates cardiovascular fate restriction and epithelial-mesenchymal transition in differentiating embryonic stem cells |
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ETS2 and MESP1 play important roles in a genetic network that governs cardiopoiesis |