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FLASH GENE
Symbol KRTAP10-5 contributors: - updated : 08-09-2005
HGNC name keratin associated protein 10-5
HGNC id 22969
Location 21q22.3      Physical location : 45.999.563 - 46.000.481
Synonym symbol(s) KAP10.5, KRTAP18-5
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
text located within introns of TSPEAR/c21orf29 gene, in a cluster of keratin-associated protein genes
STRUCTURE 917.00 kb     1 Exon(s)
regulatory sequence Promoter
Binding site   transcription factor
text structure
  • functioning intronless gene
  • binding elements for the ETS, heat shock factor, AML, and HOX families of transcription factors
    • MAPPING cloned Y linked N status provisional
    Map see KRTAP10-10
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Skin/Tegumentskin appendageshairbulb  
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Skin/Tegumenthair follicle cell
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    		several intragenic repeats
    HOMOLOGY
    Homologene
    FAMILY
  • high sulfur kerain associated proteins 10/18
    • CATEGORY structural protein
    SUBCELLULAR LOCALIZATION
    basic FUNCTION formation of a rigid and resistant hair shaft
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interacts with hair keratins
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS