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FLASH GENE
Symbol UPK3B contributors: - updated : 16-09-2004
HGNC name uroplakin 3B
HGNC id 21444
Location 7q11.2      Physical location : 76.139.744 - 76.157.197
Synonym name uroplakin IIIb
Synonym symbol(s) MGC10902, p35, UPIIIb, FLJ32198
DNA
TYPE functioning gene
STRUCTURE 17.00 kb     6 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 1625 33 320 - Deng
- - 1460 - 265 - Deng
- - 1540 - 276 - Deng
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
cells
SystemCellPubmedSpeciesStageRna symbol
Urinaryepithelial cell
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
mono polymer heteromer , dimer
HOMOLOGY
Homologene
FAMILY
CATEGORY structural protein
SUBCELLULAR LOCALIZATION     plasma membrane
    intracellular
intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
text heterodimerizing with UPBIb to exit out of endoplasmic reticulum and localized to the cell surface
basic FUNCTION
  • urothelial differentiation marker
  • may play an important role in AUM-cytoskeleton interaction
  • contributes to the formation of urothelial glycocalyx
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component component of the asymetric unit membrane (AUM) of terminally differentiated urothelial cells
    INTERACTION
    DNA
    RNA
    small molecule
    protein heterodimerizing with UPBIb to exit out of endoplasmic reticulum
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS