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FLASH GENE
Symbol TUBE1 contributors: - updated : 15-09-2004
HGNC name tubulin, epsilon 1
HGNC id 20775
Location 6q12      Physical location : 112.391.860 - 112.408.751
Synonym symbol(s) dJ142L7.2, FLJ22589, TUBE
DNA
TYPE functioning gene
STRUCTURE 16.00 kb     12 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivemale systemtestis   
cell lineage
cell lines osteogenic sarcoma cells
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
a GTP binding domain
HOMOLOGY
interspecies homolog to murine Tube1
homolog to rattus LOC361856
Homologene
FAMILY tubulin family
CATEGORY structural protein
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,cytoskeleton,microtubule,centrosome
text peri-contriolar material localization in a cell cycle dependent-manner, first associated with the older centrosome of a newly duplicated pair and then associated with both
basic FUNCTION
  • structural constituent of the cytoskeleton involved in microtubule polymerization
  • may have a GTPase activity
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule nucleotide,
    GTP binding
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS