Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | SLC29A4 | contributors: mct/npt/pgu - updated : 30-03-2016 |
HGNC name | solute carrier family 29 (nucleoside transporters), member 4 |
HGNC id | 23097 |
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Location | 7p22.1 Physical location : 5.322.560 - 5.343.702 |
Synonym name | |
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Synonym symbol(s) | ENT4, PMAT, FLJ34923 |
DNA |
TYPE | functioning gene |
STRUCTURE | 21.14 kb 11 Exon(s) |
MAPPING | cloned | Y | linked | N | status | confirmed |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Rna function | mRNA is most strongly expressed in the brain, and transcripts are also found in other organs such as the kidney, heart, and small intestine |
Type |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
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tissue |
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cells |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
physiological period | fetal |
Text | liver |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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secondary structure | with other SLC9As, share a similar tertiary structure |
HOMOLOGY |
interspecies | homolog to murine Slc29a4 (87.8 pc) |
homolog to rattus Slc29a4 (91.2 pc) |
Homologene |
FAMILY | |
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CATEGORY | transport carrier |
SUBCELLULAR LOCALIZATION | plasma membrane |
basic FUNCTION | |
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CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
text |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein |
cell & other |
REGULATION |
Other | sensitive to changes in membrane potential |
pH-dependent transporter activity (stimulated by extracellular pH from 7.4 to 6.6 and abolished by elevating extracellular pH to 8.2) |
ASSOCIATED DISORDERS |
corresponding disease(s) |
Other morbid association(s) |
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Susceptibility |
Variant & Polymorphism
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |