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FLASH GENE
Symbol KIF27 contributors: - updated : 26-03-2005
HGNC name kinesin family member 27
HGNC id 18632
Location 9q22.1      Physical location : 86.451.616 - 86.536.342
Synonym symbol(s) COS2B
DNA
TYPE functioning gene
STRUCTURE 85.00 kb     20 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Endocrinepancreas    
Respiratorylung    
Urinarykidney    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / Hematopoieticbone marrow   
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies ortholog to drosophila Costal-2
Homologene
FAMILY kinesin-like protein family. kinesin II subfamily.
CATEGORY motor/contractile
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,cytoskeleton,microtubule
intracellular,nucleus
basic FUNCTION
  • playing an important roles in intracellular transport of organelles and in cell division
  • implicated in Hedgehog pathway through the interaction with Smoothened (SMO), Fused (STK36) and microtubules
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein SMO, STK36
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS